FDA once again expands recall of blood pressure drugs

FDA once again expands recall of blood pressure drugs

July 5, 2019 Off By rzrest

The Food and Drug Administration has once again expanded its recall of widely prescribed blood pressure drugs because of contamination with a chemical linked to cancer.

The latest recall, announced Wednesday, targets 32 lots of the drug losartan sold by Macleods Pharmaceuticals. The pharmaceutical company said that it would voluntarily recall the affected batches.

Losartan is a generic angiotensin II receptor blocker, or ARB, and is used to treat high blood pressure as well as heart failure. Over the last year, scores of batches of generic ARBs have been withdrawn from the market due to the presence of chemical contaminants called nitrosamines, which have been linked to an increased risk of certain kinds of cancer.

“The FDA is continuing to work with manufacturers to swiftly remove medications from the market if they contain” unacceptable levels of nitrosamines, said Jeremy Kahn, an FDA spokesperson. “We’re continuing our investigation as part of our commitment to ensuring adequate and safe supply of ARB medicines for patients.”

Kahn told NBC News that the agency has identified 43 ARB medications that are free of nitrosamine impurities, and that this number is expected to “increase as companies continue to manufacture ARBs without nitrosamine impurities and work to replenish the U.S. supply.”

Patients who are taking an ARB should contact their pharmacist and physician to determine whether the medications they are taking are on the list, said Dr. Sadiya Khan, a cardiologist and an assistant professor of medicine at Northwestern University’s Feinberg School of Medicine in Chicago.

The FDA has compiled a list of contaminated batches that have been recalled. In addition to losartan, two other ARBs have also been affected, valsartan and irbesartan. But Khan suggests people also check with their doctors. “It can be confusing because there are a lot of different formulations of these medications out there and knowing if your medication is on the list is not clear-cut,” she said.

If a patient is currently taking one of the recalled medications, they shouldn’t worry because “there are lots of alternative blood pressure medications that patients can be switched over to,” Khan said. “The most important thing is to not stop your medication without speaking with your doctor because of the dangers of untreated blood pressure.”